Over two thirds of off-label antipsychotic prescriptions in children are for uses where there is only uncertain evidence of efficacy.

More info: The authors used physician survey data from IMS Health NDTI, a representative sample of data collection of office visits from 4,800 physicians between 1996-2008. The number of treatment visits among children that included an antipsychotic prescription increased eight-fold from 1995 to 2005 with off-label use with uncertain evidence increasing to 67%. From the source: Use of antipsychotic agents in youth younger than 18...

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Two atypical antipsychotics found to be no more effective than older antipsychotic drug

More info: A randomized, double-blind study of 116 schizophrenic or schizoaffective youth involving either olanzapine, risperidone (both atypical antipsychotics), or molindone (an older antipsychotics) failed to show a significant improvement of the atypical antipsychotics over the older antipsychotic. Citation: Jones, P. B., Barnes, T. R. B., Davies, L., Dunn, G., Lloyd, H., Hayhurst, K. B., Murray, R. M., Markwick, A., Lewis, S. W. (2006)...

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